Agonism of Prostaglandin E2 Receptor 4 Ameliorates Tubulointerstitial Injury in Nephrotoxic Serum Nephritis in Mice

Selectively targeting the E-type prostanoid receptor 4 (EP4) might be a new therapeutic option in the treatment of glomerulonephritis (GN), since the EP4 receptor is expressed on different immune cells, resident kidney cells, and endothelial cells, which are all involved in the pathogenesis of immun...

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Bibliografiske detaljer
Udgivet i:J Clin Med
Main Authors: Aringer, Ida, Artinger, Katharina, Schabhüttl, Corinna, Bärnthaler, Thomas, Mooslechner, Agnes A., Kirsch, Andrijana, Pollheimer, Marion, Eller, Philipp, Rosenkranz, Alexander R., Heinemann, Akos, Eller, Kathrin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922874/
https://ncbi.nlm.nih.gov/pubmed/33670614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10040832
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