Tim3 Is Upregulated and Protective in Nephrotoxic Serum Nephritis

T cell immunoglobulin and mucin protein-3 (Tim3) is mainly expressed on the cell surface of T-helper lymphocytes (T(H)) that negatively regulates T(H)-type 1 (T(H)-1) responses. Because blockade of Tim3 aggravates disease activity in T(H)-1–dependent diseases, we investigated whether Tim3 is involve...

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Detalhes bibliográficos
Main Authors: Schroll, Andrea, Eller, Kathrin, Huber, Julia M., Theurl, Igor M., Wolf, Anna M., Weiss, Günter, Rosenkranz, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843463/
https://ncbi.nlm.nih.gov/pubmed/20167865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090859
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