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Tim3 Is Upregulated and Protective in Nephrotoxic Serum Nephritis
T cell immunoglobulin and mucin protein-3 (Tim3) is mainly expressed on the cell surface of T-helper lymphocytes (T(H)) that negatively regulates T(H)-type 1 (T(H)-1) responses. Because blockade of Tim3 aggravates disease activity in T(H)-1–dependent diseases, we investigated whether Tim3 is involve...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843463/ https://ncbi.nlm.nih.gov/pubmed/20167865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090859 |
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