Copper Dependent Modulation of α-Synuclein Phosphorylation in Differentiated SHSY5Y Neuroblastoma Cells

Copper (Cu) dyshomeostasis plays a pivotal role in several neuropathologies, such as Parkinson’s disease (PD). Metal accumulation in the central nervous system (CNS) could result in loss-of-function of proteins involved in Cu metabolism and redox cycling, generating reactive oxygen species (ROS). Mo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Greco, Marco, Spinelli, Chiara Carmela, De Riccardis, Lidia, Buccolieri, Alessandro, Di Giulio, Simona, Musarò, Debora, Pagano, Claudia, Manno, Daniela, Maffia, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922547/
https://ncbi.nlm.nih.gov/pubmed/33670800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042038
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