BECN1 and BRCA1 Deficiency Sensitizes Ovarian Cancer to Platinum Therapy and Confers Better Prognosis

Background: BRCA1, BECN1 and TP53 are three tumor suppressor genes located on chromosome 17 and frequently found deleted, silenced, or mutated in many cancers. These genes are involved in autophagy, apoptosis, and drug resistance in ovarian cancer. Haploinsufficiency or loss-of-function of either TP...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomedicines
Egile Nagusiak: Salwa, Amreen, Ferraresi, Alessandra, Chinthakindi, Menaka, Vallino, Letizia, Vidoni, Chiara, Dhanasekaran, Danny N., Isidoro, Ciro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922320/
https://ncbi.nlm.nih.gov/pubmed/33670664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020207
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak