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Comparison of Huggins Coefficients and Osmotic Second Virial Coefficients of Buffered Solutions of Monoclonal Antibodies

The Huggins coefficient k(H) is a well-known metric for quantifying the increase in solution viscosity arising from intermolecular interactions in relatively dilute macromolecular solutions, and there has been much interest in this solution property in connection with developing improved antibody th...

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Vydáno v:Polymers (Basel)
Hlavní autoři: Pathak, Jai A., Nugent, Sean, Bender, Michael F., Roberts, Christopher J., Curtis, Robin J., Douglas, Jack F.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922252/
https://ncbi.nlm.nih.gov/pubmed/33671342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym13040601
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