The Mitochondrial Protease LonP1 Promotes Proteasome Inhibitor Resistance in Multiple Myeloma

SIMPLE SUMMARY: Multiple myeloma is the second most common cancer of the blood system in the US. Despite new therapies, a cure remains elusive, and current drugs inevitably become ineffective due to various resistance mechanisms. A frontline clinical strategy is the inhibition of the proteasome, the...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Maneix, Laure, Sweeney, Melanie A., Lee, Sukyeong, Iakova, Polina, Moree, Shannon E., Sahin, Ergun, Lulla, Premal, Yellapragada, Sarvari V., Tsai, Francis T. F., Catic, Andre
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922145/
https://ncbi.nlm.nih.gov/pubmed/33671345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040843
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