Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors

Phosphatidylethanolamine (PE) made in mitochondria has long been recognized as an important precursor for phosphatidylcholine production that occurs in the endoplasmic reticulum (ER). Recently, the strict mitochondrial localization of the enzyme that makes PE in the mitochondrion, phosphatidylserine...

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Publicat a:iScience
Autors principals: Sam, Pingdewinde N., Calzada, Elizabeth, Acoba, Michelle Grace, Zhao, Tian, Watanabe, Yasunori, Nejatfard, Anahita, Trinidad, Jonathan C., Shutt, Timothy E., Neal, Sonya E., Claypool, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921845/
https://ncbi.nlm.nih.gov/pubmed/33718843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102196
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