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Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids

The mechanical properties of the extracellular matrix strongly influence tumor progression and invasion. Yes-associated protein (YAP) has been shown to be a key regulator of this process translating mechanical cues from the extracellular matrix into intracellular signals. Despite its apparent role i...

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Detalles Bibliográficos
Publicado en:iScience
Main Authors: Illes, Bernhard, Fuchs, Adrian, Gegenfurtner, Florian, Ploetz, Evelyn, Zahler, Stefan, Vollmar, Angelika M., Engelke, Hanna
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921841/
https://ncbi.nlm.nih.gov/pubmed/33718837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102185
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