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The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context

The regulation of repair processes including base excision repair (BER) in the presence of DNA damage is implemented by a cellular signal: poly(ADP-ribosyl)ation (PARylation), which is catalysed by PARP1 and PARP2. Despite ample studies, it is far from clear how BER is regulated by PARPs and how the...

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Publicado no:Sci Rep
Main Authors: Kutuzov, M. M., Belousova, E. A., Kurgina, T. A., Ukraintsev, A. A., Vasil’eva, I. A., Khodyreva, S. N., Lavrik, O. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921663/
https://ncbi.nlm.nih.gov/pubmed/33649352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84351-1
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