Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral ureteral obstruction

Tissue kallikrein has protective function against various types of injury. In this study, we investigated whether exogenous pancreatic kininogenase (PK) conferred renoprotection in a rat model of unilateral ureteral obstruction (UUO) and H(2)O(2)-treated HK-2 cells in vitro. SD rats were subjected t...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Jin, Ji-zhe, Li, Hui-ying, Jin, Jian, Piao, Shang-guo, Shen, Xiong-hu, Wu, Yan-ling, Xu, Jia-chong, Zhang, Long-ye, Jiang, Yu-ji, Zheng, Hai-lan, Jin, Ying-shun, Cui, Sheng, Luo, Kang, Quan, Yi, Li, Can
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921586/
https://ncbi.nlm.nih.gov/pubmed/32300244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0393-7
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