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Cholesterol loading suppresses the atheroinflammatory gene polarization of human macrophages induced by colony stimulating factors
In atherosclerotic lesions, blood-derived monocytes differentiate into distinct macrophage subpopulations, and further into cholesterol-filled foam cells under a complex milieu of cytokines, which also contains macrophage-colony stimulating factor (M-CSF) and granulocyte–macrophage-colony stimulatin...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7921113/ https://ncbi.nlm.nih.gov/pubmed/33649397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84249-y |
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