Phase I study of liposomal irinotecan in patients with metastatic breast cancer: findings from the expansion phase

PURPOSE: Metastatic breast cancer (mBC) remains incurable and is associated with low survival rates. This study assessed the efficacy and safety of liposomal irinotecan in heavily pretreated patients with mBC, with or without active brain metastases (BM). METHODS: Following the dose escalation phase...

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Veröffentlicht in:Breast Cancer Res Treat
Hauptverfasser: Sachdev, Jasgit C., Munster, Pamela, Northfelt, Donald W., Han, Hyo Sook, Ma, Cynthia, Maxwell, Fiona, Wang, Tiffany, Belanger, Bruce, Zhang, Bin, Moore, Yan, Thiagalingam, Arunthathi, Anders, Carey
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2020
Schlagworte:
Clinical Trial
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921078/
https://ncbi.nlm.nih.gov/pubmed/33201358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05995-7
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