Phase I study of liposomal irinotecan in patients with metastatic breast cancer: findings from the expansion phase

PURPOSE: Metastatic breast cancer (mBC) remains incurable and is associated with low survival rates. This study assessed the efficacy and safety of liposomal irinotecan in heavily pretreated patients with mBC, with or without active brain metastases (BM). METHODS: Following the dose escalation phase...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Breast Cancer Res Treat
Autori principali: Sachdev, Jasgit C., Munster, Pamela, Northfelt, Donald W., Han, Hyo Sook, Ma, Cynthia, Maxwell, Fiona, Wang, Tiffany, Belanger, Bruce, Zhang, Bin, Moore, Yan, Thiagalingam, Arunthathi, Anders, Carey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2020
Soggetti:
Clinical Trial
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921078/
https://ncbi.nlm.nih.gov/pubmed/33201358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05995-7
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