Phase I study of liposomal irinotecan in patients with metastatic breast cancer: findings from the expansion phase

PURPOSE: Metastatic breast cancer (mBC) remains incurable and is associated with low survival rates. This study assessed the efficacy and safety of liposomal irinotecan in heavily pretreated patients with mBC, with or without active brain metastases (BM). METHODS: Following the dose escalation phase...

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Gepubliceerd in:Breast Cancer Res Treat
Hoofdauteurs: Sachdev, Jasgit C., Munster, Pamela, Northfelt, Donald W., Han, Hyo Sook, Ma, Cynthia, Maxwell, Fiona, Wang, Tiffany, Belanger, Bruce, Zhang, Bin, Moore, Yan, Thiagalingam, Arunthathi, Anders, Carey
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2020
Onderwerpen:
Clinical Trial
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921078/
https://ncbi.nlm.nih.gov/pubmed/33201358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05995-7
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