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SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging

Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular mechanism. Platelet phagocytosis by human endom...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Lan, Yong, Dong, Min, Li, Yongjun, Diao, Yongpeng, Chen, Zuoguang, Li, Yangfang
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920857/
https://ncbi.nlm.nih.gov/pubmed/33717652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.01.023
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