Immunotherapy with 4-1BBL-Expressing iPS Cell‐Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma

We have established an immune cell therapy with immortalized induced pluripotent stem-cell–derived myeloid lines (iPS-ML). The benefits of using iPS-ML are the infinite proliferative capacity and ease of genetic modification. In this study, we introduced 4-1BBL gene to iPS-ML (iPS-ML-41BBL). The ana...

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Publicado no:Int J Mol Sci
Main Authors: Kuriyama, Haruka, Fukushima, Satoshi, Kimura, Toshihiro, Kanemaru, Hisashi, Miyashita, Azusa, Okada, Etsuko, Kubo, Yosuke, Nakahara, Satoshi, Tokuzumi, Aki, Nishimura, Yuki, Kajihara, Ikko, Makino, Katsunari, Aoi, Jun, Masuguchi, Shinichi, Tsukamoto, Hirotake, Inozume, Takashi, Zhang, Rong, Nakatsura, Tetsuya, Uemura, Yasushi, Senju, Satoru, Ihn, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920470/
https://ncbi.nlm.nih.gov/pubmed/33669419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041958
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