Dysfunctional Inflammation in Cystic Fibrosis Airways: From Mechanisms to Novel Therapeutic Approaches

Cystic fibrosis (CF) is an inherited disorder caused by mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein, an ATP-gated chloride channel expressed on the apical surface of airway epithelial cells. CFTR absence/dysfunction results in defective i...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Ghigo, Alessandra, Prono, Giulia, Riccardi, Elisa, De Rose, Virginia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920244/
https://ncbi.nlm.nih.gov/pubmed/33669352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041952
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