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In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes

BACKGROUND: In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens, biomarkers, or both. In this study, we validate the EXT1/EXT2 findings in a large cohort of membranous lupus nephritis. METHODS: We...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Ravindran, Aishwarya, Casal Moura, Marta, Fervenza, Fernando C., Nasr, Samih H., Alexander, Mariam P., Fidler, Mary E., Herrera Hernandez, Loren P., Zhang, Pingchuan, Grande, Joseph P., Cornell, Lynn D., Gross, Lou Ann, Negron, Vivian, Jenson, Grace E., Madden, Benjamin J., Charlesworth, M. Cristine, Sethi, Sanjeev
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920177/
https://ncbi.nlm.nih.gov/pubmed/33478971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020081181
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