In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes

BACKGROUND: In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens, biomarkers, or both. In this study, we validate the EXT1/EXT2 findings in a large cohort of membranous lupus nephritis. METHODS: We...

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Udgivet i:J Am Soc Nephrol
Main Authors: Ravindran, Aishwarya, Casal Moura, Marta, Fervenza, Fernando C., Nasr, Samih H., Alexander, Mariam P., Fidler, Mary E., Herrera Hernandez, Loren P., Zhang, Pingchuan, Grande, Joseph P., Cornell, Lynn D., Gross, Lou Ann, Negron, Vivian, Jenson, Grace E., Madden, Benjamin J., Charlesworth, M. Cristine, Sethi, Sanjeev
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2021
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920177/
https://ncbi.nlm.nih.gov/pubmed/33478971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020081181
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