The Role of IGF/IGF-1R Signaling in Hepatocellular Carcinomas: Stemness-Related Properties and Drug Resistance

Insulin-like Growth Factor (IGF)/IGF-1 Receptor (IGF-1R) signaling is known to regulate stem cell pluripotency and differentiation to trigger cell proliferation, organ development, and tissue regeneration during embryonic development. Unbalanced IGF/IGF-1R signaling can promote cancer cell prolifera...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Ngo, Mai-Huong Thi, Jeng, Han-Yin, Kuo, Yung-Che, Nanda, Josephine Diony, Brahmadhi, Ageng, Ling, Thai-Yen, Chang, Te-Sheng, Huang, Yen-Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919800/
https://ncbi.nlm.nih.gov/pubmed/33669204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041931
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