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Niche Modulation of IGF-1R Signaling: Its Role in Stem Cell Pluripotency, Cancer Reprogramming, and Therapeutic Applications

Stem cells work with their niches harmoniously during development. This concept has been extended to cancer pathology for cancer stem cells (CSCs) or cancer reprogramming. IGF-1R, a classical survival signaling, has been shown to regulate stem cell pluripotency, CSCs, or cancer reprogramming. The me...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Chen, Pei-Chin, Kuo, Yung-Che, Chuong, Cheng-Ming, Huang, Yen-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835526/
https://ncbi.nlm.nih.gov/pubmed/33511137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.625943
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