Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease

IgE induced by type 2 immune responses in atopic dermatitis is implicated in the progression of atopic dermatitis to other allergic diseases, including food allergies, allergic rhinitis, and asthma. However, the keratinocyte-derived signals that promote IgE and ensuing allergic diseases remain uncle...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Patrick, Garrett J., Liu, Haiyun, Alphonse, Martin P., Dikeman, Dustin A., Youn, Christine, Otterson, Jack C., Wang, Yu, Ravipati, Advaitaa, Mazhar, Momina, Denny, George, Ortines, Roger V., Zhang, Emily, Miller, Robert J., Dillen, Carly A., Liu, Qi, Nolan, Sabrina J., Nguyen, Kristine, Marcello, LeeAnn, Do, Danh C., Wier, Eric M., Zhang, Yan, Caviness, Gary, Klimowicz, Alexander C., Mierz, Diane V., Fine, Jay S., Sun, Guangping, Goldbach-Mansky, Raphaela, Marusina, Alina I., Merleev, Alexander A., Maverakis, Emanual, Garza, Luis A., Milner, Joshua D., Gao, Peisong, Ramanujam, Meera, Raymond, Ernest L., Archer, Nathan K., Miller, Lloyd S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919715/
https://ncbi.nlm.nih.gov/pubmed/33645549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143334
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