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Lipotoxic Impairment of Mitochondrial Function in β-Cells: A Review
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated receptor (PPAR) signaling, enhanced oxidative str...
Gespeichert in:
| Veröffentlicht in: | Antioxidants (Basel) |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7919463/ https://ncbi.nlm.nih.gov/pubmed/33672062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020293 |
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