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Mesenchymal stem cells promote pancreatic β-cell regeneration through downregulation of FoxO1 pathway
BACKGROUND: Mesenchymal stem cells (MSC) are non-haematopoietic, fibroblast-like multipotent stromal cells. In the injured pancreas, these cells are assumed to secrete growth factors and immunomodulatory molecules, which facilitate the regeneration of pre-existing β-cells. However, when MSC are deli...
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| Publicado no: | Stem Cell Res Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7687794/ https://ncbi.nlm.nih.gov/pubmed/33239104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02007-9 |
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