Polycomb complexes redundantly maintain epidermal stem cell identity during development

Polycomb repressive complex 1 (PRC1) and PRC2 are critical epigenetic developmental regulators. PRC1 and PRC2 largely overlap in their genomic binding and cooperate to establish repressive chromatin domains demarcated by H2AK119ub and H3K27me3. However, the functional contribution of each complex to...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Cohen, Idan, Bar, Carmit, Liu, Hequn, Valdes, Victor J., Zhao, Dejian, Galbo, Phillip M., Silva, Jose M., Koseki, Haruhiko, Zheng, Deyou, Ezhkova, Elena
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2021
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919412/
https://ncbi.nlm.nih.gov/pubmed/33602871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345363.120
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