Polycomb complexes redundantly maintain epidermal stem cell identity during development

Polycomb repressive complex 1 (PRC1) and PRC2 are critical epigenetic developmental regulators. PRC1 and PRC2 largely overlap in their genomic binding and cooperate to establish repressive chromatin domains demarcated by H2AK119ub and H3K27me3. However, the functional contribution of each complex to...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Cohen, Idan, Bar, Carmit, Liu, Hequn, Valdes, Victor J., Zhao, Dejian, Galbo, Phillip M., Silva, Jose M., Koseki, Haruhiko, Zheng, Deyou, Ezhkova, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919412/
https://ncbi.nlm.nih.gov/pubmed/33602871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345363.120
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