Dihydroartemisinin Inhibits the Proliferation of Esophageal Squamous Cell Carcinoma Partially by Targeting AKT1 and p70S6K

Dihydroartemisinin (DHA), a sesquiterpene lactone with endoperoxide bridge, is one of the derivatives of artemisinin. In addition to having good antimalarial properties, DHA exhibits anticancer effects including against malignant solid tumors. However, the mechanism by which DHA inhibits the progres...

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Publicado en:Front Pharmacol
Autores principales: Zhu, Lili, Chen, Xinhuan, Zhu, Yanyan, Qin, Jiace, Niu, Tingting, Ding, Yongwei, Xiao, Yang, Jiang, Yanan, Liu, Kangdong, Lu, Jing, Yang, Wanjing, Qiao, Yan, Jin, Ge, Ma, Junfen, Dong, Ziming, Zhao, Jimin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919191/
https://ncbi.nlm.nih.gov/pubmed/33658929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.587470
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