Dihydroartemisinin Inhibits the Proliferation of Esophageal Squamous Cell Carcinoma Partially by Targeting AKT1 and p70S6K

Dihydroartemisinin (DHA), a sesquiterpene lactone with endoperoxide bridge, is one of the derivatives of artemisinin. In addition to having good antimalarial properties, DHA exhibits anticancer effects including against malignant solid tumors. However, the mechanism by which DHA inhibits the progres...

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Publicat a:Front Pharmacol
Autors principals: Zhu, Lili, Chen, Xinhuan, Zhu, Yanyan, Qin, Jiace, Niu, Tingting, Ding, Yongwei, Xiao, Yang, Jiang, Yanan, Liu, Kangdong, Lu, Jing, Yang, Wanjing, Qiao, Yan, Jin, Ge, Ma, Junfen, Dong, Ziming, Zhao, Jimin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919191/
https://ncbi.nlm.nih.gov/pubmed/33658929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.587470
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