HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs

BACKGROUND: Patients with non‐small cell lung cancer (NSCLC) harboring activating EGFR mutations are sensitive to epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐TKIs) but inevitably develop resistance to the inhibitors mostly through acquisition of the secondary T790M mutation. Al...

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Bibliographic Details
Published in:Thorac Cancer
Main Authors: Watanabe, Sho, Goto, Yasushi, Yasuda, Hiroyuki, Kohno, Takashi, Motoi, Noriko, Ohe, Yuichiro, Nishikawa, Hiroyoshi, Kobayashi, Susumu S., Kuwano, Kazuyoshi, Togashi, Yosuke
Format: Artigo
Language:Inglês
Published: John Wiley & Sons Australia, Ltd 2021
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919131/
https://ncbi.nlm.nih.gov/pubmed/33471376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13839
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