Ubiquitin Ligase SMURF2 Interacts with Filovirus VP40 and Promotes Egress of VP40 VLPs

Filoviruses Ebola (EBOV) and Marburg (MARV) are devastating high-priority pathogens capable of causing explosive outbreaks with high human mortality rates. The matrix proteins of EBOV and MARV, as well as eVP40 and mVP40, respectively, are the key viral proteins that drive virus assembly and egress...

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Veröffentlicht in:Viruses
Hauptverfasser: Shepley-McTaggart, Ariel, Schwoerer, Michael Patrick, Sagum, Cari A., Bedford, Mark T., Jaladanki, Chaitanya K., Fan, Hao, Cassel, Joel, Harty, Ronald N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918931/
https://ncbi.nlm.nih.gov/pubmed/33673144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020288
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