Ubiquitin Ligase SMURF2 Interacts with Filovirus VP40 and Promotes Egress of VP40 VLPs

Filoviruses Ebola (EBOV) and Marburg (MARV) are devastating high-priority pathogens capable of causing explosive outbreaks with high human mortality rates. The matrix proteins of EBOV and MARV, as well as eVP40 and mVP40, respectively, are the key viral proteins that drive virus assembly and egress...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Viruses
Prif Awduron: Shepley-McTaggart, Ariel, Schwoerer, Michael Patrick, Sagum, Cari A., Bedford, Mark T., Jaladanki, Chaitanya K., Fan, Hao, Cassel, Joel, Harty, Ronald N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918931/
https://ncbi.nlm.nih.gov/pubmed/33673144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020288
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