Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations

Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory cytokine with anti-fibrotic properties in toxic liver injury models and anti-steatotic functions in non-alcoholic fatty liver disease (NAFLD) attributed to the CD74/AMPK signaling pathway. As NAFLD progression is associated w...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Heinrichs, Daniel, Brandt, Elisa F., Fischer, Petra, Köhncke, Janine, Wirtz, Theresa H., Guldiken, Nurdan, Djudjaj, Sonja, Boor, Peter, Kroy, Daniela, Weiskirchen, Ralf, Bucala, Richard, Wasmuth, Hermann E., Strnad, Pavel, Trautwein, Christian, Bernhagen, Jürgen, Berres, Marie-Luise
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918903/
https://ncbi.nlm.nih.gov/pubmed/33525493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020252
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