Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations

Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory cytokine with anti-fibrotic properties in toxic liver injury models and anti-steatotic functions in non-alcoholic fatty liver disease (NAFLD) attributed to the CD74/AMPK signaling pathway. As NAFLD progression is associated w...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Heinrichs, Daniel, Brandt, Elisa F., Fischer, Petra, Köhncke, Janine, Wirtz, Theresa H., Guldiken, Nurdan, Djudjaj, Sonja, Boor, Peter, Kroy, Daniela, Weiskirchen, Ralf, Bucala, Richard, Wasmuth, Hermann E., Strnad, Pavel, Trautwein, Christian, Bernhagen, Jürgen, Berres, Marie-Luise
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918903/
https://ncbi.nlm.nih.gov/pubmed/33525493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020252
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