GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program

The in vitro reconstitution of human germ-cell development provides a robust framework for clarifying key underlying mechanisms. Here, we explored transcription factors (TFs) that engender the germ-cell fate in their pluripotent precursors. Unexpectedly, SOX17, TFAP2C, and BLIMP1, which act under th...

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Publicado en:Life Sci Alliance
Autores principales: Kojima, Yoji, Yamashiro, Chika, Murase, Yusuke, Yabuta, Yukihiro, Okamoto, Ikuhiro, Iwatani, Chizuru, Tsuchiya, Hideaki, Nakaya, Masataka, Tsukiyama, Tomoyuki, Nakamura, Tomonori, Yamamoto, Takuya, Saitou, Mitinori
Formato: Artigo
Lenguaje:Inglês
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918644/
https://ncbi.nlm.nih.gov/pubmed/33608411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000974
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