Evidence for 2-Methoxyestradiol-Mediated Inhibition of Receptor Tyrosine Kinase RON in the Management of Prostate Cancer

2-Methoxyestradiol (2-ME(2)) possesses anti-tumorigenic activities in multiple tumor models with acceptable tolerability profile in humans. Incomplete understanding of the mechanism has hindered its development as an anti-tumorigenic compound. We have identified for the first-time macrophage stimula...

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Pubblicato in:Int J Mol Sci
Autori principali: Batth, Izhar Singh, Huang, Shih-Bo, Villarreal, Michelle, Gong, Jingjing, Chakravarthy, Divya, Keppler, Brian, Jayamohan, Sridharan, Osmulski, Pawel, Xie, Jianping, Rivas, Paul, Bedolla, Roble, Liss, Michael A., Yeh, I-Tien, Reddick, Robert, Miyamoto, Hiroshi, Ghosh, Rita, Kumar, Addanki P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918140/
https://ncbi.nlm.nih.gov/pubmed/33673346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041852
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