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Pharyngeal Pumping and Tissue-Specific Transgenic P-Glycoprotein Expression Influence Macrocyclic Lactone Susceptibility in Caenorhabditis elegans

Macrocyclic lactones (MLs) are widely used drugs to treat and prevent parasitic nematode infections. In many nematode species including a major pathogen of foals, Parascaris univalens, resistance against MLs is widespread, but the underlying resistance mechanisms and ML penetration routes into nemat...

詳細記述

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書誌詳細
出版年:Pharmaceuticals (Basel)
主要な著者: Gerhard, Alexander P., Krücken, Jürgen, Neveu, Cedric, Charvet, Claude L., Harmache, Abdallah, von Samson-Himmelstjerna, Georg
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917992/
https://ncbi.nlm.nih.gov/pubmed/33668460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14020153
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