Complexation with Random Methyl-β-Cyclodextrin and (2-Hidroxypropyl)-β-Cyclodextrin Enhances In Vivo Anti-Fibrotic and Anti-Inflammatory Effects of Chrysin via the Inhibition of NF-κB and TGF-β1/Smad Signaling Pathways and Modulation of Hepatic Pro/Anti-Fibrotic miRNA

Chrysin (CHR) is a natural flavonoid with a wide range of pharmacological activities, including hepatoprotection, but poor water solubility. By including water-soluble hydroxypropyl (HPBCD) and randomly methylated (RAMEB) β-cyclodextrin, we aimed to increase its biodisponibility and the effectivenes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ciceu, Alina, Balta, Cornel, Herman, Hidegard, Gharbia, Sami, Ignat, Simona-Rebeca, Dinescu, Sorina, Váradi, Judit, Fenyvesi, Ferenc, Gyöngyösi, Szilvia, Hermenean, Anca, Costache, Marieta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917810/
https://ncbi.nlm.nih.gov/pubmed/33668543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041869
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados