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A Single Point Mutation, Asn(16)→Lys, Dictates the Temperature-Sensitivity of the Reovirus tsG453 Mutant
Studies of conditionally lethal mutants can help delineate the structure-function relationships of biomolecules. Temperature-sensitive (ts) mammalian reovirus (MRV) mutants were isolated and characterized many years ago. Two of the most well-defined MRV ts mutants are tsC447, which contains mutation...
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| Publicado no: | Viruses |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7917769/ https://ncbi.nlm.nih.gov/pubmed/33673179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020289 |
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