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The eukaryotic replisome tolerates leading‐strand base damage by replicase switching
The high‐fidelity replicative DNA polymerases, Pol ε and Pol δ, are generally thought to be poorly equipped to replicate damaged DNA. Direct and complete replication of a damaged template therefore typically requires the activity of low‐fidelity translesion synthesis (TLS) polymerases. Here we show...
Gorde:
| Argitaratua izan da: | EMBO J |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7917549/ https://ncbi.nlm.nih.gov/pubmed/33555053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020107037 |
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