Vanillic Acid Reduces Pain-Related Behavior in Knee Osteoarthritis Rats Through the Inhibition of NLRP3 Inflammasome-Related Synovitis

Objectives: Synovitis plays an important role in knee osteoarthritis (KOA) pain. The activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in fibroblast-like synoviocytes (FLSs) promotes KOA development. In this study, we aimed to investigate whether vanillic acid (VA), a monomer derive...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Ma, Zhenyuan, Huang, Zhengquan, Zhang, Li, Li, Xiaochen, Xu, Bo, Xiao, Yancheng, Shi, Xiaoqing, Zhang, Haosheng, Liao, Taiyang, Wang, Peimin
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917290/
https://ncbi.nlm.nih.gov/pubmed/33658936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.599022
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki