Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-Specific Olfactory Impairment in Mice

Epidemiological and experimental studies have associated oral and systemic exposures to the herbicide paraquat (PQ) with Parkinson’s disease. Despite recognition that airborne particles and solutes can be directly translocated to the brain via olfactory neurons, the potential for inhaled PQ to cause...

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Veröffentlicht in:Toxicol Sci
Hauptverfasser: Anderson, Timothy, Merrill, Alyssa K, Eckard, Matthew L, Marvin, Elena, Conrad, Katherine, Welle, Kevin, Oberdörster, Günter, Sobolewski, Marissa, Cory-Slechta, Deborah A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Neurotoxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916739/
https://ncbi.nlm.nih.gov/pubmed/33372994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa183
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