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Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-Specific Olfactory Impairment in Mice

Epidemiological and experimental studies have associated oral and systemic exposures to the herbicide paraquat (PQ) with Parkinson’s disease. Despite recognition that airborne particles and solutes can be directly translocated to the brain via olfactory neurons, the potential for inhaled PQ to cause...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Anderson, Timothy, Merrill, Alyssa K, Eckard, Matthew L, Marvin, Elena, Conrad, Katherine, Welle, Kevin, Oberdörster, Günter, Sobolewski, Marissa, Cory-Slechta, Deborah A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916739/
https://ncbi.nlm.nih.gov/pubmed/33372994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa183
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