Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice

The pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) is not fully understood, but evidence is accumulating that immune dysfunction plays a significant role. We previously reported that 31-week-old Tnfaip3(DNGR1-KO) mice develop pulmonary hypertension (PH) symptoms. These mice harbor...

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Publicado en:Int J Mol Sci
Autores principales: van Uden, Denise, Koudstaal, Thomas, van Hulst, Jennifer A. C., Bergen, Ingrid M., Gootjes, Chelsea, Morrell, Nicholas W., van Loo, Geert, von der Thüsen, Jan H., van den Bosch, Thierry P. P., Ghigna, Maria-Rosa, Perros, Frédéric, Montani, David, Kool, Mirjam, Boomars, Karin A., Hendriks, Rudi W.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916474/
https://ncbi.nlm.nih.gov/pubmed/33578743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041756
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