Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice

The pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) is not fully understood, but evidence is accumulating that immune dysfunction plays a significant role. We previously reported that 31-week-old Tnfaip3(DNGR1-KO) mice develop pulmonary hypertension (PH) symptoms. These mice harbor...

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Publicat a:Int J Mol Sci
Autors principals: van Uden, Denise, Koudstaal, Thomas, van Hulst, Jennifer A. C., Bergen, Ingrid M., Gootjes, Chelsea, Morrell, Nicholas W., van Loo, Geert, von der Thüsen, Jan H., van den Bosch, Thierry P. P., Ghigna, Maria-Rosa, Perros, Frédéric, Montani, David, Kool, Mirjam, Boomars, Karin A., Hendriks, Rudi W.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916474/
https://ncbi.nlm.nih.gov/pubmed/33578743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041756
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