Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice

Dopamine is a key neurotransmitter that regulates attention through dopamine D1 and D2-receptors in the prefrontal cortex (PFC). We previously developed an object-based attention test (OBAT) to evaluate attention in mice. Disruption of the dopaminergic neuronal system in the PFC induced attentional...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Wulaer, Bolati, Kunisawa, Kazuo, Tanabe, Moeka, Yanagawa, Aika, Saito, Kuniaki, Mouri, Akihiro, Nabeshima, Toshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Micro Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916264/
https://ncbi.nlm.nih.gov/pubmed/33640003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00760-3
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