Identification of RSV Fusion Protein Interaction Domains on the Virus Receptor, Nucleolin

Nucleolin is an essential cellular receptor to human respiratory syncytial virus (RSV). Pharmacological targeting of the nucleolin RNA binding domain RBD1,2 can inhibit RSV infections in vitro and in vivo; however, the site(s) on RBD1,2 which interact with RSV are not known. We undertook a series of...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Mastrangelo, Peter, Chin, Allysia A., Tan, Stephanie, Jeon, Amy H., Ackerley, Cameron A., Siu, Karen K., Lee, Jeffrey E., Hegele, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915953/
https://ncbi.nlm.nih.gov/pubmed/33567674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020261
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