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Identification of RSV Fusion Protein Interaction Domains on the Virus Receptor, Nucleolin

Nucleolin is an essential cellular receptor to human respiratory syncytial virus (RSV). Pharmacological targeting of the nucleolin RNA binding domain RBD1,2 can inhibit RSV infections in vitro and in vivo; however, the site(s) on RBD1,2 which interact with RSV are not known. We undertook a series of...

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Dettagli Bibliografici
Pubblicato in:Viruses
Autori principali: Mastrangelo, Peter, Chin, Allysia A., Tan, Stephanie, Jeon, Amy H., Ackerley, Cameron A., Siu, Karen K., Lee, Jeffrey E., Hegele, Richard G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915953/
https://ncbi.nlm.nih.gov/pubmed/33567674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020261
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