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Exogenous NAD(+) Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 Signaling

Cell senescence is accompanied by decreased nicotinamide adenine dinucleotide (NAD(+)) levels; however, whether exogenous NAD(+) affects bone marrow-derived mesenchymal stem cells (BMSCs) senescence and the involved mechanisms is still unclear. Here, we find that exogenous NAD(+) replenishment signi...

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Publicado en:Antioxidants (Basel)
Main Authors: Wang, Jie, Liu, Lin, Ding, Zhongjie, Luo, Qing, Ju, Yang, Song, Guanbin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915830/
https://ncbi.nlm.nih.gov/pubmed/33562281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020254
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