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Amino Acylguanidines as Bioinspired Catalysts for the Asymmetric Aldol Reaction

The binding and stabilizing effect of arginine residues in certain aldolases served as inspiring source for the development of a family of amino acylguanidine organocatalysts. Screening and optimization led to identify the threonine derivative as the most suitable catalyst for the asymmetric aldol a...

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Détails bibliographiques
Publié dans:Molecules
Auteur principal: Jimeno, Ciril
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915246/
https://ncbi.nlm.nih.gov/pubmed/33562560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040826
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