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Yeasts as Complementary Model Systems for the Study of the Pathological Repercussions of Enhanced Synphilin-1 Glycation and Oxidation

Synphilin-1 has previously been identified as an interaction partner of α-Synuclein (αSyn), a primary constituent of neurodegenerative disease-linked Lewy bodies. In this study, the repercussions of a disrupted glyoxalase system and aldose reductase function on Synphilin-1 inclusion formation charac...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Seynnaeve, David, Mulvihill, Daniel P., Winderickx, Joris, Franssens, Vanessa
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915245/
https://ncbi.nlm.nih.gov/pubmed/33562355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041677
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